Avondlezing door prof.dr. S. Brandenburg, georganiseerd door de Groningse Chemische Kring.
The development of radiotherapy with high energy X-rays has resulted in a significant improvement of the cure rate of localized tumors. This has been achieved by a combination of better target coverage and reduction of the radiation induced complications caused by the inevitable co-irradiation of the normal tissues surrounding the tumor.
Nevertheless, radiation induced complications are still a limiting factor in the treatment of many patients. Given the nature of the interaction of X-rays with matter there is little room for further reduction of the radiation dose to the normal tissues. The solution for the treatment of these patients therefore has to be found in the use of another radiation modality: protons and other ions.
In the talk I will compare radiotherapy with high energy X-rays and ions from a physics perspective; present the technology for radiotherapy with in particular protons, which has now become commercially available from several manufacturers and discuss the on-going research to fully exploit the physics-based advantages of using ions instead of X-rays in radiotherapy.
Sytze Brandenburg is professor in accelerator physics at the University of Groningen.
After studying physics in Groningen and Helsinki, Finland he did his PhD research in experimental nuclear physics at the Kernfysisch Versneller Instituut (KVI), Groningen, the Netherlands.
From 1986 to 1994 he worked at the Institut de Physique Nucléaire, Orsay, France on the design, construction and commissioning of the superconducting cyclotron AGOR, that is operational at the KVI-CART since 1996.
He currently directs the medical physics group of the KVI-Center for Advanced Radiation Technology that, in collaboration with several departments of the UMCG, performs R&D on the applications of ionizing radiation in health care and more in particular radiotherapy with ion beams. He has been strongly involved in the development of the Groningen Proton Therapy Center at the UMCG-campus that started patient treatment in the beginning of 2018 and is now fully operational.
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